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Similarly, an animal study on cocks demonstrated that Mn supplementation led to a decline in reproductive hormone levels ( in vitro studies have reported a wide range of Mn-induced pulmonary effects, including lung damage, inflammation, alveolar macrophage infiltration, and oxidative stress ( Additionally, excessive Mn has been linked to metabolic disorders, including type II diabetes, obesity, and cardiovascular disease, with oxidative stress proposed as a key contributing factor ( 6 Disease modulation of Mn transport and metabolism Mn transport and metabolism are dynamically regulated across diverse disease states

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However, food sources alone are rarely enough to maintain good skin health